Local doctors warn that the frigid temperatures are worse for children.
Wind Chill temperatures over the next two days could dip as low as -50.
Dr. Joe Tzougros of the ProHealth Medical Clinic in Pewaukee said, "None of us are physiologically designed to tolerate this temperature."
Tzougros says children are even more susceptible to hypothermia or frostbite, "the tiny children have more body surface area to cover compared to their entire mass."
Tzougros recommends parents look to the American Academy of Pediatrics for cold weather safety tips.
"We think we can tough anything around here, we're used to cold weather and we want to enjoy the winter we can. But there are days like this where it's more dangerous than your average winter cold day," Tzougros said.
First responders are also prepared for cold weather calls. Justin Malueg of Bell Ambulance says they expect to see 15 to 20 additional cold weather calls a day.
Inside the ambulance are additional items to combat the cold weather including kits that heat the IV's.
"We're just trying to reverse the effects of hypothermia, actively rewarming the core body temperature from the inside" said Malueg.