Autopsies on the two men found dead in a Potawatomi Hotel room were completed Tuesday.
The two men were in town from Canada for a softball tournament run by the Saturday Softball League and the North American Gay Amateur Athletic Alliance.
In the 16th floor hotel room, investigators found rolled up bills and a powder that tested positive for traces of fentanyl; a strong drug in the opioid family.
"There are certainly really good mucus membranes in the nasal passage to absorb a drug and get it there quickly," said Sara Schreiber with the Medical Examiner's Office.
The wife of one of the men said he had done drugs in the past, but was not taking anything currently. She said he smoked marijuana and did mushrooms, cocaine and ecstasy. There was no mention of opioids.
"When you administer a drug like an opiate to someone that doesn't have that tolerance and your body doesn't know how to deal with that," Schreiber said. "They are used to a different substance. That can be toxic or fatal to them because of that naive exposure."
Eric Peterson is the tournament director for the Dairyland Classic. This season was its 39th annual tournament. Many of the nearly 400 players stayed at the Potawatomi Hotel for the weekend.
However, while many were heading home Monday morning, the team from Toronto learned of the tragedy.
"They woke up in the morning intending to have breakfast and driving back to Toronto," Peterson said. "That obviously didn't happen when their two friends didn't come to breakfast with them."
The tournament had both gay and straight players, including one of the two men found dead at the hotel.
"If you know anything about the opioid epidemic, it knows no boundaries," Peterson said. "It knows no borders, no race, no sex, no gender, no sexual orientation, it has no identity. It doesn't care. Opioids are a deadly thing. They want to harm you."
Peterson likens this to the AIDS epidemic. He says it's about raising awareness in the LGBT community to discuss the dangers of using this drug.
"We have to have an understanding that we don't have to party with drugs to have a great time," Peterson said. "We can have a fulfilling life, that's wonderful, has meaning, purpose and has social connections without turning to drug use."